Save Postman requests in a collection (e.g., "fast.API course") to avoid accidental loss. Save individual requests (e.g., "get posts," "create post") within the collection for easy access, even after closing Postman. Collections preserve request details, including body content. This segment demonstrates how to organize and save API requests within Postman collections for easy access and management. The speaker clearly shows the steps involved in creating a new collection, naming it, and then saving individual GET and POST requests into that collection. This is valuable for anyone working with APIs, as it ensures that requests are not lost and can be easily retrieved later, even after closing the Postman application.